Analysis of Brain Lesions (ABLe) in MEDx

The Analysis of Brain Lesions module is now in MEDx 3.4. It is a tool for characterizing lesions in MRI or CT Images of the adult human brain.

Module Functionality

  • Determination of the lesion volume

  • Spatial normalization of the input brain into Talaraich space

  • Percent of total brain volume

  • Quantification of Brodmann Area intersections

  • Reporting routines allowing for group lesion display


Algorithms and Methods

  • Automated Image Registration (AIR v.3.08) used for spatial normalization

  • Brodmann Areas displayed on slices derived from Damasio Atlas

  • Netscape used to display HTML reports.


The development of ABLe was a collaborative effort between Medical Numerics, Inc., the Cognitive NeuroScience Section at the National Institute of Neurological Disorders and Stroke, and the Diagnostic Radiology Department at the United States National Institutes of Health.

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